MCQ
Alkaptonuria is a disease where the urine is:
  • A
    Yellow
  • B
    White
  • C
    Orange
  • D
    Black

Answer

  1. Black

Explanation:

Alkaptonuria is an inherited condition that makes urine  black when exposed to air. Mutations in the HGD gene cause alkaptonuria. Homogentisic acid, which is produced when phenylalanine and tyrosine are broken down, accumulates in the body. Excess homogentisic acid is deposited in connective tissues, which causes cartilage and skin to darken. Over time, a buildup of this substance in the joints leads to arthritis. Homogentisic acid is also excreted in urine, making the urine turn dark when exposed to air.

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