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Molecular Basis of Inheritance — BIOLOGY STD 12 Science — Question

Gujarat BoardEnglish MediumSTD 12 ScienceBIOLOGYMolecular Basis of Inheritance2 Marks
Question
Based on your understanding of genetic code, explain the formation of any abnormal hemoglobin molecule. What are the known consequences of such a change?
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Answer

Normally human beings have following types of hemoglobin, $\mathrm{Hb}^{\mathrm{A}}, \mathrm{Hb}^{\mathrm{A} 2}$ and Hb . Alteration in genes for beta chain on hemoglobin results in formation of $\mathrm{Hb}^{\mathrm{S}}$ type of hemoglobin. This type of hemoglobin molecule is responsible for sickle cell anemia.

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