Question
Define the following terms as related to proteins:
  1. Peptide linkage.
  2. Primary structure.
  3. Denaturation.

Answer

  1. Peptide linkage is an amide formed between $–COOH$ group and $–NH_2$ group $(-CO-NH-)$.
  2. Specific sequence of amino acids in a polypeptide chain is said to be the primary structure of the protein.
  3. When a protein in its native form, is subjected to change in temperature or change in pH, protein loses its biological activity. This is called denaturation of protein.

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