Question
Explain the Translocation type of chromosomal aberration. Translocation

Answer

The transfer of a segment of the chromosome to a non-homologous chromosome is called translocation. Translocation should not be confused with crossing over, in which an exchange of genetic material between homologous chromosomes takes place. Translocation occurs as a result of the interchange of chromosome segments in non-homologous chromosomes.
There are three types:
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  1. Simple translocation
  2. Shift translocation
  3. Reciprocal translocation
i. Simple translocation: A single break is made in only one chromosome. The broken segment gets attached to one end of a non-homologous chromosome. It occurs very rarely in nature.ii. Shift translocation: A broken segment of one chromosome gets inserted interstitially in a non-homologous chromosome.iii. Reciprocal translocations: It involves the mutual exchange of chromosomal segments between two non-homologous chromosomes. It is also called illegitimate crossing over. It is further divided into two types.a. Homozygous translocation: Both the chromosomes of two pairs are involved in translocation. Two homologous of each translocated chromosomes are identical.b. Heterozygous translocation: Only one of the chromosome from each pair of two homologous are involved in translocation, while the remaining chromosome is normal. Translocations play a major role in the formation of species.

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