- Both assertion and reason are true, but reason is not the correct explanation of assertion
Explanation:
The differences between initiation step of protein synthesis in eukaryotes and prokaryotes are : (i) In prokaryotes initiation factors are three IF1, IF2 and 1F3. Eukaryotes have at least ten initiation factors - eIF1, eIF2, eIF3, eIF4A, eIF4B eIF4C, eIF4D, eIF4F eIF5 and eIF6
(ii) In eukaryotes, fonnylation of methionine does not take place. In prokaryotes tRNA is charged with formylated methionine. (iii) The larger subunit of ribosome combines with 40 S- mRNA-tRNA Met (in case of prokaryotes, 30 S) complex to form intact ribosome. It requires initiation factor IF1 in prokaryotes and factors eIF1 eIF4 (A, B, C) in eukaryotes.