MCQ
For question two statements are given$-$one labelled Assertion and the other labelled Reason. Select the correct answer to these questions from the codes $(a), (b), (c)$ and $(d)$ as given below.
Assertion : Spleen can be thought of as an immunologic conference centre.
Reason: Spleen helps only in digestion.
  • A
    Both assertion and reason are true and reason is the correct explanation of assertion.
  • B
    Both assertion and reason are true, but reason is not the correct explanation of assertion.
  • Assertion is true, but reason is false.
  • D
    Both assertion and reason are false.

Answer

Correct option: C.
Assertion is true, but reason is false.
The spleen is an immunologic filter of blood. It is made up of $B-$cells, $T-$cells, macrophages, dendritic cells, natural killer cells and red$-$blood cells. In addition to capturing foreign materials $($antigens$)$ from the blood that passes through the spleen, migratory macrophages and dendritic cells bring antigens to the spleen via blood stream. An immune response is initiated when the macrophages or dendritic cells present the antigen to the appropriate $B$ or $T-$cells. This organ can be thought of as an immunological conference centre. In the spleen, $B-$cells become activated and produce large amounts of antibody.

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