MCQ
Gene therapy for the first time was clinically done for:
- AADA deficiency.
- BRheumatoid fever.
- CDiabetes.
- DAlzheimer's disease.
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List $I$ $(syndrome)$
$(1)$ Patau’s syndrome
$(2)$ Kline-Felter’s syndrome
$(3)$ Down’s syndrome
$(4)$ Turner’s syndrome
List $II$ $(Chromosomal\, abnormality)$
$(A)$ $44 + XXY = 47$
$(B)$ $44 + X = 45$
$(C)$ $46 + 1 = 47$, Chromosome $13^{th}$
$(D)$ $46 + 1 = 47$, Chromosome $21^{st}$ Code

$II.$ The cell is treated with specific concentration of a divalent cation such as $... B...$ to increase pore size in cell wall
$III. $In $...C...$ method recombinant $DNA$ is directly injected into the nucleus of an animal cell
The most appropriate option regarding $\mathrm{A}, \mathrm{B}$ and $\mathrm{C}$ is