Question
How does a chromosomal disorder differ from a Mendelian disorder?
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Answer
| S. No. | Mendelian disorder | Chromosomal disorder |
| (i) | This disorder is mainly due to alteration or mutation in the single gene. | This disorder is caused due to absence or excess or abnormal arrangement of one or more chromosomes. |
| (ii) | This follows Mendel’s principles of inheritance. | This does not follow Mendel’s principles ofinheritance. |
| (iii) | This may be recessive or dominant in nature. | This is always dominant in nature. |
| (iv) | For example, haemophilia, sickle–cell anaemia. | For example, Turner’s syndrome. |
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