How does a chromosomal disorder differ from a Mendelian disorder? - Vidyadip

Question

How does a chromosomal disorder differ from a Mendelian disorder?

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Answer

S. No.	Mendelian disorder	Chromosomal disorder
(i)	This disorder is mainly due to alteration or mutation in the single gene.	This disorder is caused due to absence or excess or abnormal arrangement of one or more chromosomes.
(ii)	This follows Mendel’s principles of inheritance.	This does not follow Mendel’s principles ofinheritance.
(iii)	This may be recessive or dominant in nature.	This is always dominant in nature.
(iv)	For example, haemophilia, sickle–cell anaemia.	For example, Turner’s syndrome.

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