Explanation:
As we know that there are only four nucleotides namely deoxyadenosine, deoxyguanosine, deoxythymidine and deoxycytidine. Further, there are 20 essential amino acids that are to be encoded by these four nucleotides.
A triplet code could make a genetic code for 64 different combinations (4 × 4 × 4) genetic code. A code of single nucleotides would give only four amino acids to be translated. The doublet code would code for 16 amino acids (4 × 4).
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Reason : Sex in humans is a polygenic trait depending upon a cumulative effect of some genes on $X-$ chromosome and some on $Y-$ chromosome.
Reason : $DNA$ binds around histone proteins that form a pool and the entire structure is called a nucleosome.