$(i)$ Enzymes lack in nucleophilic groups
$(ii)$ Enzymes are highly specific both in binding chiral substrates and in catalyzing their reactions
$(iii)$ Enzymes catalyse chemical reactions by lowering the activation energy
$(iv)$ Pepsin is a proteolytic enzyme
| List $I$ Vitamin | List $II$ Deficiency disease |
| $A$ Vitamin $A$ | $I.$ Beri-Beri |
| $B$ Thiamine | $II.$ Cheilosis |
| $C$ Ascorbic acid | $III.$ Xeropthalmia |
| $D$ Riboflavin | $IV.$ Scurvy |
Choose the correct answer from the options given below:

