Read the following and answer any four questions from (i) to (v) given below:
Transgenic animals can serve as factories that in some cases, may produce large amount of proteins more efficiently. Transgenic mice have been engineered to express human antibodies by introducing large segment of human DNA encoding human immunoglobulin genes. In transgenic large animals such as cow or sheep proteins of pharmaceutical value can be produced in large quantities in milk which is later purified. Transgenesis can be used to alter many phenotypic properties including growth rate, fat composition, milk production, hair texture, etc.
- The production of transgenic animals includes
- Identification and separation of desired gene.
- Combining the desired gene with appropriate vector.
- Introduction of vector in cells, tissues or embryos.
- All of these.
- In transgenic animals, i.e., cow and sheep proteins of pharmaceutical value are produced in large quantities in the
- Blood.
- Accumulated fat.
- Mammary glands.
- None of these.
- Mouse is mostly preferred animal for studies on gene transfer because.
- Short oestrous cycle.
- Long gestation period.
- Short generation time.
- Production of one or two offspring per pregnancy.
- Both (A) and (C)
- Both (A) and (B)
- Only D
- Both (C) and (D).
- Transgenic genes alter many phenotypic properties including:
- Growth rate.
- Fat composition.
- Milk production.
- All of these.
- Assertion: Transgenic mice have been engineered to express human antibodies.
Reason: Large segment of human DNA encoding human immunoglobulin have been transferred to mice.
- Both assertion and reason are true and reason is the correct explanation of assertion.
- Both assertion and reason are true but reason is not the correct explanation of assertion.
- Assertion is true but reason is false.
- Both assertion and reason are false.
