MCQ
The components of nucleotide are-
- A$N _2$ Base and pentose sugar
- B$N _2$ Base and phosphate group
- ✓$N _2$ Base, pentose sugar and phosphate group
- D$N _2$ Base, pentose sugar and carboxylic group
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$I$. In the absence of adenosine deaminase enzyme, purine metabolism is disturbed and $T-$lymphocytes fails to function $II$. $ADA$ deficiency is caused by the deletion of the gene for $ADA$
$III$. In some cases, it can be cured by bone marrow transplantation and enzyme replacement therapy. But in both approaches, the patients are not completely cured
$IV$. For permanent cure, genes isolated from the bone marrow cells producing $ADA$ at early embryonic stages can be a possible cure
Which of the above statements are correct?
$I.$ Recombinant $DNA$ technology popularly known as genetic engineering is a stream of biotechnology which deals with the manipulation of genetic material by man in vitro
$II. pBR322$ is the first artificial cloning vector developed in $1977$ by Boliver and Rodriquez from $E$. coli plasmid
$III.$ Restriction enzymes belong to a class of enzymes called nucleases
Which of the statements given above are correct?