Fill in the blanks
(i) Sickle-cell anaemia is caused by the substitution of A by B at 6th position of the C globin chain of Haemoglobin.
(ii) In phenylketonuria, the individual lacks an enzyme that converts the amino acid phenylalanine into D.
(iii) Failure of segregation of chromatids during cell division cycle results in the gain or loss of a chromosome called E.
(iv) In F, there is an increase in a whole set of chromosome in an organism.
(v) Down's syndrome is genetic disorder because of presence of an additional copy of chromosome number G.
(vi) In H syndrome, there is an additional copy of X-chromosome resulting into a karyotype of 47, XXY.
(vii) In I syndrome, there is an absence of one of the X-chromosome, i.e. 45 with XO.
(viii) The traits that are generally controlled by 3 or more genes are called J traits.
(ix) When single gene exhibit multiple phenotypic expression, it is called K gene.
(x) In honey bee, females are L having M chromosome and males are N having 16 chromosome. This is called O sex-determination system.
(xi) Colour blindness is P - linked Q disorder. This defect is due to mutation in certain genes present in R chromosome.
(xii) Thalassemia is S-linked T disease. It is controlled by two closely linked genes U and Von chromosome W of each parent.
choose the correct option given below :-