Importance of plasma protein: 90-92 percent water and 6-8 percent protein substances are found in plasma. Fibrinogen, globulin, and albumin are the main proteins present in plasma. Fibrinogen is necessary for blood clotting or coagulation. Globulin is used for the body's immune system, and albumin is used for maintaining osmotic balance. Hence, we can say how important plasma protein is for us.