Question
Why do lepidoplerans die when they feed on Bt cotton plant? Explain how does it happen.
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Answer
Bt cotton contains inactive toxin protein/protoxin/insecticidal protein/crystal protein, once the insect ingest it the inactive protoxins are converted into active form due to alkaline pH in gut, which solubilise the crystals, activated toxins binds to surface of midgut (epithelial cells), create pores causes cell swelling, lysis eventually leading the death of the insect pest.
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