Question
Why do you see two different types of replicating strands in the given DNA replication fork? Explain. Name these strands.
Why do you see two different types of replicating strands in the given DNA replication fork? Explain. Name these strands.
✓
Answer
- Both the strands of parent DNA function as template strands.
- On the template strand with 3' → 5' polarity, the new strand is synthesised as a continuous stretch as the DNA polymerase can carry out polymerisation of the nucleotides only in 5' → 3' direction; this is called continuous synthesis and the strand is called leading strand.
- On the other template strand with 5 → 3' polarity, the new strand is synthesised from the point of replication fork, also in 5' → 3' direction, but in short stretches; they are later joined by DNA-ligases to form a strand, called lagging strand.
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