Question
Why is diffusion insufficient to meet the oxygen requirement of multicellular organisms like humans?

Answer

In multicellular organisms like human, all the cells are not in direct contact with the surrounding environment. The body structure is more complex and the body size is also large. Therefore, simple diffusion will not be sufficient to send oxygen to every cell. It has been estimated that a period of 3 years would be needed to carry a molecule of O2 from our lungs to reach our toes through diffusion.
So, diffusion is insufficient to meet the oxygen requirement of multicellular organisms like humans.

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