Question
Distinguish between: Zona pellucida and Corona radiata.

Answer

Zona pellucidaCorona radiata
1. Zona pellucida is inner, thin and transparent layer surrounding the secondary oocyte.1. Corona radiata is the outer thick layer surrounding the secondary oocyte.
2. Zona pellucida is a non-cellular layer.2. Corona radiata is a cellular layer.
3. Zona pellucida is secreted by the ovum itself.3. Corona radiata is formed by follicular cells which are glued together by hyaluronic acid.
4. Zona pellucida is retained for more time after fertilization till the ovum gets implanted in the uterus.4. Corona radiata is retained till the ovum gets fertilized.
5. Zona pellucida is digested by zona lysine or acrosin at the time of fertilization.5. Corona radiata is digested by hyaluronidase enzyme at the time of fertilization.

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(1) Alu I(a) 5′ G-A-A-T-T-C 3′ 3′ C-T-T-A-A-G 5’
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