Question
Explain parasitism as population interaction with examples.
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Reason: Prokaryotic RNA polymerase has sigma $(\sigma)$ factor.
Which of the above given materials are required for transcription?

| S no. | Reema | Jai | Ankit |
| (a) | Diabetes | Grave's disease | Rheumatic fever |
| (b) | Pernicious anaemia | Multiple sclerosis | Myasthenia gravis |
| (c) | Addison's disease | Rheumatoid arthritis | Hashismoto's thyroiditis |
| (d) | Systemic lupus erythematosus | Severe combined immunodeficiency disease | AIDS |
Reason: Monoclonal antibodies have been successfully used in the treatment of autoimmune disease.

Assuming a single base pair substitution has occurred, what is the mRNA code in the affected mutant?
Normal A-G-C-A-T-G-G-A-T-C-C-T
Mutant A-G-C-A-T-G-C-A-T-C-C-T
The table shows six codons and the corresponding amino acids into which each is translated.| mRNA codon | Amino acid |
| AAG | Lysine |
| CUA | Leucine |
| GGA | Glycine |
| GUA | Valine |
| UAC | Tyrosine |
| UCG | Serine |
Reason: Reading frame remains unaltered with insertion or deletion of three or its multiple bases.
| Normal haemoglobin | Sickle cell haemoglobin |
| Thr-Pro-Glu-Glu | Thr-Pro-Val-Glu |

