Bihar BoardEnglish MediumSTD 12 ScienceBIOLOGYBiotechnology: Principles and Processes3 Marks
Question
find out how to distinguish between: Plasmid DNA and chromosomal DNA
✓
Answer
Plasmid DNA and Chromosomal DNA: Plasmids are extra-chromosomal structures which keep multiplying automatically inside bacteria. Their DNA is made up of two strands and is usually circular. Apart from other genes, genes involved in replicating the plasmid are also found on them. Plasmids used in recombinant DNA technology also contain antibiotic resistance genes, which make identification of recombinant DNA molecules possible. The DNA present in chromosomes is chromosomal DNA. It also has two strands but is not spherical and is located in the nucleus of the cell. It does not contain genes for antibiotic resistance. This DNA is longer and contains more nucleotides than plasmid.
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