For a double strand $DNA$, one strand is given below:

The amount of energy required to split the double strand $DNA$ into two single strands is . . . .kcal $mol ^{-1}$.

[Given: Average energy per $H$-bond for $A - T$ base pair $=1.0 kcal mol ^{-1}, G - C$ base pair $=1.5 kcal mol ^{-1}$, and $A - U$ base pair $=1.25 kcal mol ^{-1}$. Ignore electrostatic repulsion between the phosphate groups.]

Q: For a double strand $DNA$, one strand is given below: The amount of energy required to split the double strand $DNA$ into two single strands is . . . .kcal $mol ^{-1}$. [Given: Average energy per $H$-bond for $A - T$ base pair $=1.0 kcal mol ^{-1}, G - C$ base pair $=1.5 kcal mol ^{-1}$, and $A - U$ base pair $=1.25 kcal mol ^{-1}$. Ignore electrostatic repulsion between the phosphate groups.]

d $A = T \quad 2 H$-bond $G \equiv C \quad 3 H$-bond Number of $A = T$ pair $=7$ Number of $G \equiv C$ pair $=6$ Number of $H$-bond involve in $A = T =7 \times 2=14$ Number of $H$-bond involve in $G \equiv C =6 \times 3=18$ Energy required for $A = T =14 \times 1=14$ Energy required for $G \equiv C =18 \times 1.5=27$ Total energy required $14+27=41$

Question

For a double strand $DNA$, one strand is given below:

The amount of energy required to split the double strand $DNA$ into two single strands is . . . .kcal $mol ^{-1}$.

[Given: Average energy per $H$-bond for $A - T$ base pair $=1.0 kcal mol ^{-1}, G - C$ base pair $=1.5 kcal mol ^{-1}$, and $A - U$ base pair $=1.25 kcal mol ^{-1}$. Ignore electrostatic repulsion between the phosphate groups.]

A$20$
B$30$
C$40$
D$41$

IIT 2024, Medium

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