Biotechnology and its Applications BIOLOGY - Biotechnology and its Applications

1. NBPGR
2. NSC
3. NIPGR
4. GEAC

1. Is a method of synthesising human protein from human DNA
2. Uses restriction enzymes
3. Can produce billions of copies of a DNA fragment
4. Takes place naturally in bacteria

1. Agent for production of dairy products.
2. Source of industrial enzyme.
3. Indicator of water pollution.
4. Insecticide.

1. Bacteria are resistant to the toxin.
2. Toxin is immature.
3. Toxin is inactive.
4. Bacteria encloses toxin in a special sac.

1. Substrate
2. Analyte
3. Antibody
4. None of the above

1. Bone marrow.
2. Lymphocytes.
3. Blood plasma.
4. Monocytes.

1. 1,00,000
2. 40,000
3. 21,000
4. 10,000

1. Exposure to X-ray to rectify the defective gene
2. Replacing the defective gene with a functional gene
3. Oral delivery of genes
4. Use of therapeutic medicines to rectify the defective genes

1. E. coli
2. Brassica napus
3. Bacillus thuringiensis
4. Agrobacterium

1. Bioremediation
2. Chemical safety
3. Vaccine safety
4. Toxicity test

1. The production of transgenic animals includes

1. Identification and separation of desired gene.
2. Combining the desired gene with appropriate vector.
3. Introduction of vector in cells, tissues or embryos.
4. All of these.

2. In transgenic animals, i.e., cow and sheep proteins of pharmaceutical value are produced in large quantities in the

1. Blood.
2. Accumulated fat.
3. Mammary glands.
4. None of these.

3. Mouse is mostly preferred animal for studies on gene transfer because.

1.  Short oestrous cycle.
2. Long gestation period.
3. Short generation time.
4. Production of one or two offspring per pregnancy.

1. Both (A) and (C)
2. Both (A) and (B)
3. Only D
4. Both (C) and (D).

4. Transgenic genes alter many phenotypic properties including:

1. Growth rate.
2. Fat composition.
3. Milk production.
4. All of these.

5. Assertion: Transgenic mice have been engineered to express human antibodies.

Reason: Large segment of human DNA encoding human immunoglobulin have been transferred to mice.

1. Both assertion and reason are true and reason is the correct explanation of assertion.
2. Both assertion and reason are true but reason is not the correct explanation of assertion.
3. Assertion is true but reason is false.
4. Both assertion and reason are false.

1. How is mature insulin different from proinsulin secreted by pancreas in humans?
2. Explain how was human functional insulin produced using rDNA technology.
3. Why is the functional insulin thus produced considered better than the ones used earlier by diabetic patients?